2023 BOOK--"Schizophrenia and Genetics: The End of an Illusion"
As psychiatric genetic theories and claims continue to unravel in the face of DNA-based failure, a detailed explanation of why they are unraveling.
Published by Routledge
In Schizophrenia and Genetics: The End of an Illusion (Routledge, 2023), psychologist Jay Joseph shows that the evidence from family, twin, adoption, and DNA-based (molecular genetic) research that psychiatry ceaselessly puts forward in support of schizophrenia (better characterized as “psychosis”) as a “highly heritable disorder” is stunningly weak. This conclusion has major implications for how we prevent, view, and intervene on schizophrenia/psychosis, as well as other psychiatric conditions. Science is about data, but more importantly, about how scientists and others interpret data and the stories they tell about it. Science (and psychiatry) is currently experiencing a “replication crisis” that has called into question decades of publications, leading to the retraction of tens of thousands of scientific research articles. A key aspect of the replication crisis is p-hacking, the practice of researchers consciously or unconsciously manipulating definitions, data, and comparisons, either openly or behind the scenes, to transform non-findings into publishable “findings” that fall below the conventional .05 level of statistical significance. In addition to showing that behavioral twin study assumptions are false and that no causal “genes for schizophrenia” have been found after more than 50 years of attempts to identify them, Joseph shows that the most frequently cited “landmark” schizophrenia adoption studies were massively and openly p-hacked. He argues, therefore, that these adoption studies should be retracted. Joseph tells a dramatically different story about 100+ years of schizophrenia genetic research from the one that students and the public usually hear. He concludes that causal “schizophrenia genes” are unlikely to exist, with the hope of helping inspire new generations of critical thinkers prepared to reevaluate the causes of psychiatric conditions and human behavioral differences.
I haven´t read you Book yet, but I think it is important People and Readers are clearly and knowingly aware All mental Disorders diagnoses, some call them Mental Labels not diagnoses, are made not with Objective Methods, but with InterSubjective Methods they call under some guise of Observers´ Agreement Correlations.
Agreements which are in Fact, beyond doubt, agreements of Subjectivities, which cannot lead to Objectiveness, never, at all. Even if aggregated ad nauseam and cross correlated more than the Pilgrims Bandwagons CrissCrossed California Centuries ago...(Paraphrased from the Movie the "Odd Couple 2").
Such is because all Intersubjective and Subjective claims lack causality, some cannot be correlated if not because in Subjectivity and Intersubjectivity connections are not seen nor established with Objectiveness, , those are not Real connections in the sense of the word Reality.
But are connected by mere will of the Subjects: are fabricated by them. Those connections in Subjectivity and InterSubjectivity are artificial and do not represent Real connections.
One thing to be wary of: Objectiveness and Objective in Science and Empiricism are not related to the use of the word Objectivity in Philosophy.